I direct the Machine Learning and Healthcare Lab at Johns Hopkins University. We are interested in enabling new classes of diagnostic and treatment planning tools for healthcare—tools that use statistical machine learning techniques to tease out subtle information from "messy" observational datasets, and provide reliable inferences for individualizing care decisions. In order to accomplish these goals, our lab (1) identifies domains/disease areas where such approaches can make an impact, (2) identifies gaps where current technologies fail, (3) designs new statistical machine learning techniques that solve associated fundamental computational challenges, and (4) develops and deploys solutions to measure impact.